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Further, the colloidal stability of the formulation in circulation and membrane destabilization and hexagonal phase II conversion following exposure to the acidic TME due to the presence of DOPE (37.5%) in the liposome membrane could contribute to the enhanced Dox release within the tumor tissue 17

Donepezil was administered intraperitoneally (i.p.) at a dose of 3 mg/kg, as per established protocols 9

McKeown NM, Meigs JB, Liu S, Saltzman E, Wilson PW, Jacques PF (2004) Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham offspring cohort

Tsaousis, A

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