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When performed by experienced surgeons in expert centers, discoid excision is considered safe, with postoperative complication rates of 24.5% (mostly minor Clavien-Dindo grades I-II) and no severe complications like rectovaginal fistula or anastomotic leakage reported (60)

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Similarly, the inhibitory effect of ASA on Complex IV activity was more pronounced in GSH-depleted cells

(2018) found that an acidic environment increased the expression of DMT1 in microglia and increased the uptake of non-transferrin-conjugated iron

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