Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Product Name 2-[4-(carboxymethyl)piperazin-1-yl]acetic acid dihydrochloride

Product Name 2-[4-(carboxymethyl)piperazin-1-yl]acetic acid dihydrochloride Synonyms CAS Number 127178-07-8 Related CAS 5430-78-4 Molecular Formula C8H16Cl2N2O4 Molecular Weight 275

Chloroquinaxoline sulfonamide (CQS) share the same mechanism of action as Indisulam

The Val–Cit dipeptide is optimized for cathepsin B cleavage in lysosomal environments

no side reactions occur – the label and detection tags react selectively and specifically with one another

Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C79H112FN11O25 Molecular Weight 1634

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Product Name 2-[4-(carboxymethyl)piperazin-1-yl]acetic acid dihydrochlorideSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload