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To further develop therapeutic targets, we tested the efficacy of N -acetyl cysteine (NAC), an antioxidant and anti-inflammatory agent in ameliorating the extent of myocardial damage and also investigated if facilitated repair could be augmented in a rat model of left anterior descending artery ligation-induced MI

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Titration governs tolerability fast 2-week ramp to 15 mg gave 24.5% AE-discontinuation (Frias 2018)

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