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BM-MSCs or BM-MSCs-exosome co-treatment caused anti-apoptotic impacts via a meaningful reduction in Bax/Bcl2 ratio and a rise in the expression of mitochondrial mitophagy genes, including Parkin RBR E3 Ubiquitin Protein Ligase ( Parkin ), phosphatase and tensin homolog (PTEN)-induced putative kinase 1 ( PINK1 ), unc-51 like autophagy activating kinase 1 ( ULK1 ), B-cell lymphoma 2/adenovirus E1B 19 kDa protein-interacting protein 3 ( BNIP3L ), autophagy related gene ( ATG5 ), ATG7 and ATG12

The study of succinate as an oncometabolite has only recently begun, and more research needs to be conducted to completely understand its tumorigenic properties

In glr1 cells, the simple proteins (helixloophelix conformation with two disulphides) so far identified as targets for Mia40 do not exhibit changes in their levels which in past studies served as a measure for the efficiency of the Mia40 import pathway (Chacinska et al , 2004

Although these methods provide valuable structural and compositional insights, they are less suitable for measuring zinc dynamics in organelles (Table 3)

A low concentration of vitamin E is frequently observed in cerebrospinal fluid (CSF)