DACF1 Binder Building Block 1 glue Product Name Thalidomide-C3-PEG4-OH Synonyms Thalidomide-4'-C3-PEG4-OH

Product Name Thalidomide-C3-PEG4-OH Synonyms Thalidomide-4'-C3-PEG4-OH CAS Number n/a Related CAS Molecular Formula C24H32N2O9 Molecular Weight 492

Roy Burman

NCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and a C-terminal 7-Amino-4-methylcoumarin (AMC) moiety

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DACF1 Binder Building Block 1 glue Product Name Thalidomide-C3-PEG4-OH Synonyms Thalidomide-4'-C3-PEG4-OHBuilding Block for DACF1 Binders and PROTACs based on DACF1 Binders. Product Name DACF1 Binder Building Block 1 Synonyms CAS Number n a Related CAS Molecular Formula C31H41ClN6O2 Molecular Weight 565. 16 SMILES CC(C)(C)OC(=O)NCCNC1=NC(=NC2=CC(=CC=C12)N1CCNCC1)C1(CCCCC1)C1=CC=C(Cl)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For