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PDI protein was also readily detected in the hepatocytes, and its level in hepatocytes was markedly reduced in APAP-damaged hepatocytes around the central vein, and joint treatment with cystamine restored its protein levels in these hepatocytes (Fig

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However, protein expression of NRF2 and its Ser40 phosphorylated form did not alter (Ferenczi et al., 2020)

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Autoimmune conditions like rheumatoid arthritis or lupus can increase susceptibility to costochondritis