MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC)

167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

324 SMILES CC(C)(C)OC(=O)N1CCN(CCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl N-{2-[2-(piperazin-1-yl)ethoxy]ethyl}carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C13H27N3O3 Molecular Weight 273

Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C100H150N14O25 Molecular Weight 1948

Product Name Lenalidomide-PEG4-C2-azide Synonyms Lenalidomide-4'-PEG4-C2-azide CAS Number 2399455-55-9 Related CAS Molecular Formula C23H32N6O7 Molecular Weight 504

MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 167 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C(O)=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,