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Data were analyzed using the 2 Ct method with TATA box binding protein (TBP) as a housekeeping gene and expressed as fold change relative to the controls

Its underlying mechanisms are multifaceted, encompassing genetic variations, environmental influences, cerebral artery constriction, abnormalities in monoamine neurotransmitters, oxidative stress, mitochondrial disturbances, the involvement of calcitonin gene-related peptide (CGRP), neurogenic inflammation, and broader neuroinflammation (6)

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