4-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}butanoic acid amine 86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC)

86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and oligonucleotides

32 SMILES Cl

921 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne

4-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}butanoic acid amine 86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC)Nitrogen Heterocycle Based Linker (NHBL). Binfunctional amine carboxylic acid linker. Product Name 4 {4 [(tert butoxy)carbonyl]piperazin 1 yl}butanoic acid Synonyms CAS Number 1240619 81 1 Related CAS Molecular Formula C13H24N2O4 Molecular Weight 272. 345 SMILES CC(C)(C)OC(=O)N1CCN(CCCC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement