Thalidomide-5'-O-PEG6-OH deuterium-labeled-heterocycle Degradation of CCNK/CDK12 is a

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer

Product Name Pomalidomide-CO-C3-alkyne Synonyms Pomalidomide-4'-CO-C3-alkyne CAS Number n/a Related CAS Molecular Formula C19H17N3O5 Molecular Weight 367

369 SMILES BrCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

ACS Chemical Biology 2020

Product Name Pomalidomide-PEG2-OH Synonyms Pomalidomide-4'-PEG2-OH CAS Number 2143097-10-1 Related CAS Molecular Formula C17H19N3O6 Molecular Weight 361

Thalidomide-5'-O-PEG6-OH deuterium-labeled-heterocycle Degradation of CCNK/CDK12 is aDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide 5' O PEG6 OH Synonyms CAS Number n a Related CAS Molecular Formula C25H34N2O11 Molecular Weight 538. 55 SMILES OCCOCCOCCOCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions