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When ARA-290 binds to the IRR, it does two critical things: It shuts down inflammation: It tells the immune system to stop attacking the damaged area, switching the focus from "defense" to "reconstruction." It stimulates regeneration: It promotes the sprouting of small nerve fibers, which are often the first to die in conditions like Small Fiber Neuropathy (SFN)

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After being closed with 5% skimmed milk for 1 h, the membrane was incubated overnight at 4C with the following primary antibodies: YTHDF1, Cytochrome C, mitochondrial transcription factor A (TFAM), Ferritin, glutathione peroxidase 4 (GPX4), and -actin

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