Azide-Lys(m-PEG4)-Val-Cit-PAB-PNP mal-propionyl CC-92480 promotes rapid and extensive

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM

NCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Journal of Enzyme Inhibition and Medicinal Chemistry

Product Name CP-Cy5 Synonyms SNAP2-Cy5 CAS Number Related CAS Molecular Formula C44H50ClN6O2 Molecular Weight 730

Azide-Lys(m-PEG4)-Val-Cit-PAB-PNP mal-propionyl CC-92480 promotes rapid and extensiveSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine