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Description

Which intracellular signalling pathways does IGF-1 LR3 activate via IGF-1R

Jiang R, Chen JH, Jin J, Shen W, Li QM

Although a plethora of macrophage phenotypes has been identified by the advent of single cell biology - amongst others resident macrophages, TNF + pro-inflammatory macrophages, IL1 + pro-inflammatory macrophages, Trem2 + macrophages, lipid-associated Trem2 hi-perilipin + macrophages, and IL10 + TNFAIP3 + macrophages (de Winther et al., 2023