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Description

This metabolic flexibility allows Tregs to maintain suppressive function in lactate-rich, hypoglycemic niches, while their immunosuppressive capacity is impaired by glucose restoration (240)

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Therefore, exploring the combined application of NNMTi with other interventions has become a research hotspot in recent years

Maffeo E, Montuschi A, Stura G, Giordana MT (2014) Chronic acquired hepatocerebral degeneration, pallidal T1 MRI hyperintensity and manganese in a series of cirrhotic patients