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HDL cholesterol and apolipoprotein A-I (apo A-I) mediate cholesterol efflux in antigen-presenting cells (APCs), thereby altering lipid raft structure and reducing T cell activation [82]

To interrogate this, we utilized an AAV-TBG-Cre viral delivery system, which produces liver-specific Cre expression and subsequent genetic deletion 49,50

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This enzyme has also been identified as a cause of familiar forms of amyotrophic lateral sclerosis (ALS) due to copper homeostasis is altered

Rights and permissions About this article Cite this article Muoz-Jurado, A., Escribano, B.M., Caballero-Villarraso, J