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Similar to RFK KO and FLAD1 KO cells, we observed decreased levels of untagged FSP1 and FSP1GFP proteins and increased sensitization to ferroptosis upon GPX4 inhibition under vitamin-B2-deficient conditions (Extended Data Fig

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The finding underscores the need for pre-specified monitoring plans, routine competency maintenance, incident reporting, and subgroup performance auditspractical accountability mechanisms that complement efficacy trials and help prevent unintended harms during post-deployment use

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Tissue distribution Tissue distribution studies in rodent models suggest BPC-157 distributes broadly with notable accumulation in GI mucosa (consistent with its biological origin as a gastric-juice fragment)

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