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P., Udoh, K

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d h , Quantification of PMA-induced NETs formation (100 nM, 6 h) in WT and XKR8-deficient neutrophils after pre-incubation with various inhibitors: Tempol (30 M) ( d , n = 12), DPI (10 M) ( e , n = 11), GSK2795039 (10 M) ( f , n = 12), Enzastaurin (10 M) ( g , n = 12), U0126 (10 M), GW5074 (10 M) ( h , n = 12)

Suramin, a century-old drug used to treat African sleeping sickness and river blindness, can effectively inhibit SARS-CoV-2 polymerase activity with at least 20-fold more activity than RDV-3Pi in biochemical assays and inhibits viral replication in vitro 141

PloS One (2012) 7(2):e32094