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The ROS is a single summary of the effect of smoking on the outcome, with higher positive ROSs corresponding to stronger and more consistent evidence and a higher average effect size of smoking and a negative ROS, suggesting that, based on the available evidence, there is no significant effect of smoking on the outcome after accounting for between-study heterogeneity

Users might experience irritation to the lungs, eyes and throat as well as rash, headache, diarrhea and abdominal pain

Niki Holder is light and easy to throw away cigarette ash

Adjustable Airflow Slider Seamlessly dial from tight, mouth-to-lung draws to airy, direct-lung hits

Like so many things, it was taken by Europeans and used along with opium, tea, and coffee for medicinal and recreational purposes