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181 SahaP.KatarkarA.DasB.BhattacharyyaA.ChaudhuriK

Regorafenib (RGF), a multi-kinase inhibitor approved by the FDA, is often prescribed to patients with metastatic CRC who no longer respond to first-line treatments

It increases the number of beneficial bacteria, such as Parvibacter, Enterorhabdus, and Akkermansia , attenuating the inflammatory response in DSS-induced mouse models (Cheng et al., 2023)