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Tirzepatide works because it directly modulates appetite signaling and insulin dynamics through receptor binding that has been validated in multiple Phase 3 randomised controlled trials

Cota D, Steiner MA, Marsicano G, Cervino C, Herman JP, Grubler Y, Stalla J, Pasquali R, Lutz B, Stalla GK, Pagotto U

As an additional example to that of the trefoil peptides noted above, the peptide EGF (epidermal growth factor) is produced in human milk to promote growth of the gastrointestinal tract in newborn infants, but the same peptide aggressively stimulates the growth of breast cancer cells in adults

saturated fats and monounsaturated fats seem to be better tolerated (60)

Immunity 53, 11681181 e7