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The investigator collected, verified completed diary cards, and qualified staff interviewed participants to assess the occurrence of unsolicited AEs, serious adverse events (SAEs), and adverse events of special interest (AES)

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4 Carnitine and oxidative stress It has been widely shown that clinically significant oxidative stress takes place in patients with advanced cancer, as shown by augmented levels of reactive oxygen species (ROS) and decreased levels of glutathione peroxidase [45, 46]