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Parkinsonism Relat Disord 20:2731 Marie A, Darricau M, Touyarot K, Parr-Brownlie LC, Bosch-Bouju C (2021) Role and mechanism of vitamin A metabolism in the pathophysiology of Parkinsons disease

In educational frameworks, DSIP is positioned at most for the patient with documented, persistent sleep-architecture problems who has genuinely failed sleep hygiene, CBT-I, and melatonin, and who explicitly understands they would be engaging with something investigational rather than a validated treatment