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(Peptide Sciences) While senescence is protective in acute contexts (e.g., preventing malignant transformation, wound repair), the accumulation of senescent cells over time is detrimental: They occupy tissue space and resources, impairing progenitor cell function

For example, if a phase I metabolite cant be cleared out quickly enough with phase II conjugation, then it can cause oxidative stress

This process is essential for maintaining the delicate balance of sulfur compounds in our bodies

New insights into pathomechanisms and treatment possibilities for lung silicosis