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However, other investigators have reported that high glucose levels can activate NAD(P)H oxidases in vascular cells independent of mitochondrial metabolism [14]

Werner, C

Front Immunol 5:630 Pollizzi KN, Powell JD (2015) Regulation of T cells by mTOR: the known knowns and the known unknowns

Heme oxygenase-1 (HO-1) cytoprotective pathway: A potential treatment strategy against coronavirus disease 2019 (COVID-19)-induced cytokine storm syndrome

As systemic metabolic function improves, secondary benefits such as enhanced muscle definition, improved skin tone, and overall physical refinement may be observed, reflecting improved cellular energy balance and reduced inflammatory burden