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BPC-157 exerts potent anti-inflammatory effects by modulating the immune response, reducing cytokine production, and inhibiting inflammatory pathways

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We found that treatment with cisplatin alone significantly increased caspase-8 activity, whereas pretreatment with bucillamine markedly decreased the catalytic activity of caspase-8 to the level similar to the control or bucillamine alone, suggesting that activities of both caspase-3 and -8 are downregulated by bucillamine in the presence of cisplatin