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doi: 10.3389/fphar.2015.00001 Received 08 October 2014 Accepted 05 January 2015 Published 10 March 2015 Volume 6 - 2015 Edited by Alfonso Pompella, University of Pisa, Italy Reviewed by Peter James King, Queen Mary University of London, UK

These are all manifestations of the havoc wreaked by free radicals

Nauen R, Bass C, Feyereisen R, Vontas J

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Lee J., Kim T., Yang H., Bae S.H

Although oral therapy with the least toxic of these compounds, glutathione monoethyl ester, did raise erythrocyte and white blood cell glutathione levels in a few affected patients (W Rhead, unpublished results), it also provoked moderate gastrointestinal irritation resulting in vomiting and diarrhea, largely precluding oral therapy with this compound or other related molecules containing free sulfhydryls