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This is thought to affect angiogenic activity, fibroblast behavior, and collagen organization in tissue repair models

A phase II trial involving capmatinib and nabulizumab as secondary treatments for advanced/metastatic EGFR wild-type NSCLC patients, who had not received anti-PD-1/PD-L1 before, revealed that a group with elevated MET expression (evidenced by immunohistochemistry in 50% of tumor cells = 3 + or gene copy number (GCN) 5 or IHC in METex14 + = 2 +) exhibited a six-month PFS rate of 68.9%

The researchers then assessed the potential action of Ipamorelin on the contractility of gastric smooth muscle induced by acetylcholine and electrical field stimulation