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WADA updates Ongoing changes: Testing becoming more sophisticated Detection windows extending More peptides added to banned list For athletes: Assume all performance-enhancing peptides will be detectable

Its potential anti-aging benefits and ability to reduce chronic inflammation have also been noted, although these effects require further validation in human studies

More RCTs where subjects are stratified into individual metabotypes are needed to elucidate whether gut microbial metabolites are the bioactive compounds responsible for the effects

Chemistry Compound JMF4073, Tert-butyl 4-(2-(5-fluoro-3-oxobenzo[d]isothiazol-2(3H)-yl) acetyl) piperazine-1-carboxylate, was synthesized using 2,5-difluorobenzonitrile as the starting materials