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In addition, the release of low concentrations of Cu 2 by copper-based nanozymes can activate the anti-inflammatory signal pathway, induce macrophages to transform from M1 type to M2 type, inhibit chronic inflammation, and promote collagen deposition [243]

Initiator or non-initiator enzymes are crucial for the production of short peptides and amino acids that are the building blocks of the taste compounds found in cheese, whereas coagulant enzymes are primarily in charge of hydrolyzing caseins into big or intermediate peptides

SCH51344, though not used clinically, led to the identification of crizotinib, a widely used dual Met/ALK inhibitor, as a potent inhibitor of MTH1 activity

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Cardiolipin can be oxidized by ROS or by the cardiolipincytochrome c complex (Kagan et al., 2005)