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In a recent dose-response study of Zhang et al

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Mitochondria cannot manufacture glutathione de novo , so glutathione is synthesized in the cytosol and a small fraction of the total cellular pool is then imported into the mitochondrial matrix by carrier-mediated transport (22

Cerebrovascular diseases have been associated with cognitive decline and dementia (c.f., vascular dementia (63)), and represent a common comorbidity with significant impacts on the onset and progression of NDDs (64, 65)

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