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Additionally, there was a lower number of neutrophils in the low-dose CB+LPS (-1.0x10 5 cells, 95% CI: -1.6x10 5 to -0.3x10 5 cells) and high-dose group CB+LPS (-0.6x10 5 cells, 95% CI: -1.3x10 5 to -0.02x10 5 cells) groups as compared to the LPS group

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Figure 1 In terms of alpha diversity computed at the level of ASVs, toddlers have the lowest values for the Shannon index and the Chao1 richness estimator throughout the sampling period

13.1%, p =0.03) than NUCs alone, but not in mild cases ( p =0.50)