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Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle

Nature 2011 472(7341):40 - 41 M

232 Interestingly, PTEN degradation also occurs independently of H 2 O 2 , as observed in pancreatic cancer cells with elevated prostaglandin production via 5-LOX and COX-2 overexpression