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Description

The underlying mechanism of APAP hepatotoxicity is thought to be conversion of APAP to N-acetyl-p-benzoquinone imine (NAPQI), which is mediated by members of the cytochrome P450 family, especially CYP2E1

120 A 12-week placebo-controlled trial examined the safety of combining aged garlic extract with warfarin therapy

J Clin Invest 52(3):741744

By reducing oxidative stress and stabilizing mitochondrial membranes, SS-31 enhances mitochondrial function, potentially mitigating heart failure and improving cardiac energy metabolism