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These approaches, from conventional drug combinations to novel immunomodulatory and non-antifungal partnerships, represent a promising advance in antifungal therapeutics

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doi: 10.1016/j.biomaterials.2018.09.007 95 WuZPanYWangZDingPGaoTLiQet al

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This trade-off has been observed in Culex mosquitoes, where local frequencies of resistant and wild-type backgrounds rise and fall in response to seasonal insecticide usage 13