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These findings suggest the presence of a compensatory pathway present in cells expressing both IR and IGF-1R through which loss of insulin generated signals triggers increased signaling via IGF-1/IGF-1R

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A., Smuckler, E

In support of a role of phototransduction for thermal tolerance, genes from this pathway have previously been linked to laboratory selection for high temperature tolerance in D

Moreover, total tomato GST enzyme activity was also found to be significantly enhanced in response to salinity, dehydration and osmotic stresses