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Obeticholic acid, a semisynthetic bile acid analog, is an agonist of the farnesoid X receptor, which has anti-inflammatory and antioxidant activities (155)

In addition, compelling evidence suggests that DNA damage response (DDR) signaling is a predominant mechanism associated with the build-up of DNA damage, aging, and cell senescence (Malaquin et al., 2015)

Given the limited effective therapies, the treatment of this disease is not ideal and its incidence and prevalence are increasing

Reading product labels and knowing the right ingredient to look for helps us become informed and smart consumers

Increased levels of oxidized proteins and nitrated tyrosine residues within the -synuclein have been found in Lewy bodies in patients with PD