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HCV and oxidative stress in the liver

During the normal metabolism of cells, the body is exposed to exogenous chemical carcinogens and irradiation

After cell transplantation, soluble signals activating hepatic stellate cells are rapidly induced along with early up-regulated expression of matrix metalloproteinases and their inhibitors [140]

Biochem J 473(7):805825 Davin LB, Lewis NG (2000) Dirigent proteins and dirigent sites explain the mystery of specificity of radical precursor coupling in lignan and lignin biosynthesis