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For example, with human cancer cell lines, Se-konjac glucomannan performed anti-proliferation properties against human lung cancer cells (A549) and human breast cancer cells (HCC1937) by activating mitochondria pro-apoptosis protein caspase-3 ( Table 3 shows positive results on the biological properties of Se-enriched plants and some food ingredients (microalgae, probiotics bacteria and milk casein) in the in vivo animal models compared with Se-enriched yeast, an alternative source of SeMet (around 60-84%) with a lower toxic effect ( Auricularia auricular mushroom and Se-enriched radish sprouts, showed similar effects on improving antioxidant activities such as GPx and catalase, lower malondialdehyde (MDA) levels, and protecting liver damages in high-fat diet mice ( Astragalus also has anti-inflammatory effects on diabetic mice by lower serum inflammation-related proteins, including C-reactive protein, tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6) and nuclear factor kappa B (NFB) ( Pyracantha fortuneana , and Se-enriched sweet potato inhibited tumor growth via apoptosis pathway and decreased IL-2, TNF-, and VEGF in mice xenograft with human cancer tumor ( TABLE 3 In vivo studies of Se-enriched plants and other food materials using animal models

Kruis W, Fric P, Pokrotnieks J, et al

But, the role of glutathione in both health and disease has been extensively studied, and its understood that a chronically low glutathione level is associated with higher mortality

Sodium ascorbate and calcium ascorbate are the most common forms, although a number of other mineral ascorbates are available

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