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The nicotinamide mononucleotide (NMN), a phosphorylated intermediate in the synthesis of NAD can also be considered as a precursor since exogenous NMN administration raises NAD levels in various cell lines and tissues [68], and an NMN transporter (Slc12a8) has recently been identified in the murine small intestine [69]

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They grow large but immature, a condition called megaloblastic anaemia

It is thought that lower levels influence impaired wound healing and immune dysfunction among other age-related declines