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SKU: 2292855196
Price: 28.49 USD
Availability: InStock
Rating: 4.2493 (29 reviews)

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Description

PMID 10075906

J.BrandtL

In ob/ob mice and Zucker rat models, it has consistently reduced fat mass, decreased epididymal and brown adipose tissue weight, and improved lipid profiles without affecting lean tissue or glucose homeostasis

Mitochondrial Ca 2+ handling is also disrupted, leading to the opening of the mitochondrial permeability transition pore (mPTP) and the release of cytochrome c, which triggers apoptosis