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It can release paracrine (direct effects on neighboring structures through diffusion) and/or endocrine adipokines, inflammatory factors (both pro- and anti-inflammatory), miRNAs, and other molecules influencing vascular homeostasis

Gut microbiome health index (GMHI) is a robust indicator for assessing the health status of gut microbiota, which was higher in HC group (Supplementary Fig

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Although, currently there is no management against PsO, the disease has been much improved in management because to the development of targeted medicines made possible by advances in our understanding of its underlying mechanisms