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When NaBPC157 was given 10 minutes after the application of the combination of L-NAME + L-arginine (still led to a blood pressure increase), its clear effect (noted in L-NAME treated rats) disappeared

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Its dramatic age-related decline is significant: plasma concentrations average 200 ng/mL at age 20 but typically plummet to 80 ng/mL by age 60a 60% reduction correlating with visible aging and reduced healing capacity

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