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allergens or environmental pollutants can also promote ROS production 12,14,16

The acute gout model and treatment in rats All procedures involving animals were conducted in strict compliance with the Animal Management Regulations set forth by the Ministry of Health of the Peoples Republic of China and adhered to the Southern Medical Universitys Guidelines for the Care and Use of Experimental Animals

Bakaeen FG, Jaroszewski DE, Rice DC, Walsh GL, Vaporciyan AA, Swisher SG , Benjamin R, Blackmon S, Reardon MJ

We first outline the mechanisms by which RT induces anti-tumor immunity, with a focus on RT-mediated activation of the cGAS-STING pathway in tumor cells and the associated immunosuppressive effects of RT

Mechanistically, SAC directly interacts with Keap1 to promote Nrf2 into the nucleus, enhance the transcription of antioxidant genes (such as GPX4 and NQO1), and restore the biosynthesis of GSH