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It may promote tissue repair, support blood vessel growth, reduce inflammation, and aid muscle, tendon, and ligament recovery

Pickart and Margolina (2018) review documents broad gene-expression effects in vitro

Identification: Look for their distinctive coloration and shape, especially the shield-like structure on the back of females

In biochemical and preclinical models, the peptide appears to regulate endothelial activity, cell migration, and cytoskeletal organization through interactions with kinase signaling cascades and nitric oxide related mechanisms

Int J Cardiol 198:15 Johnsen SP, Hundborg HH, Srensen HT et al (2005) Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke