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In the iris, CTGF is observed in both the sphincter and dilator muscles, and in the vessels of the iris and ciliary body, where it is derived from vascular endothelium but not from vascular smooth muscle cells (83)

[14] stato accertato che ALCAR accresce la motilit degli spermatozoi, probabilmente in conseguenza di un incremento dei livelli plasmatici di testosterone, in quanto favorisce un maggior rilascio di ormone luteinizzante

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This mutation was mainly observed in GBM, present in 3 GBM cases out of 8 patient samples with this mutation (cBioportal, COSMIC study - 329 COSU329 Glioblastoma Multiforme, TCGA), and was also observed in lung squamous cell carcinoma, clear cell renal cell carcinoma, colon adenocarcinoma, liver neoplasm and prostate carcinoma (Table S4)

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