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IBD - Crohn disease Causes The exact cause of Crohn disease is unknown

After treatment, some people may improve significantly and be able to discontinue treatment without relapse

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Animal toxicology studies lasting up to 9 months (in non-human primates) found no significant organ toxicity, genotoxicity, or reproductive toxicity

It achieves a much higher drug concentration in the mucosa with a more rapid onset of action and better efficacy than oral 5-ASA monotherapy or rectal steroids alone[25]