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Support for healthy collagen production

The results showed that MOX, alone or with Cu 2+ , caused oxidative stress, and growth and locomotion impairments, which were closely associated with the dysregulation of stress-responsive, neuromuscular-related, and apoptosis-related genes

VALOR was a phase III, randomized, double-blind, placebo-controlled study that has evaluated the efficacy, safety, tolerability, and pharmacodynamic effects of tofersen on ALS with a confirmed SOD1 mutation (NCT02623699)