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Patients with severe forms of COVID-19 infection characterized by a hyperinflammatory state due to the cytokine storm may develop an acute hypothalamus/pituitary/thyroid axis dysfunction that may cause both acute hypothyroidism and immune-mediated damage (127)

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Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the akt/GSK3-/NFAT Axis

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Kolevzon A, Angarita B, Bush L, Wang AT, Frank Y, Yang A, et al

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