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3.3.1 Individual use of nanoparticles in ferroptosis-mediated disease The injection of DFO in a model of Idiopathic pulmonary fibrosis (IPF) was found to increase survival (from 50% to 90%) and reverse the IPF phenotype in mice

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Vaccines 7 , 745752 (2008)

We speculate that in the presence of functional DNA repair mechanisms and physiological levels of FA, FA-caused DNA damage would be alleviated before it reaches the threshold required for triggering apoptosis